EFFICIENT SYNTHESIS AND DIRECTION OF METHYLATION OF 2-METHYLQUINAZOLINE-4(3H)-THIONE
DOI:
https://doi.org/10.5281/zenodo.7865906Keywords:
alkylation reaction, 2-Methylquinazolin-4-one, methyl iodide, dimethylsulfate, alcohol, dipolar DMFA, methylating agent, 1,3-dimethylquinazolin-4-one.Abstract
The alkylation reaction of 2-Methylquinazolin-4-one with methyl iodide and dimethylsulfate in alcohol was studied. When aprotic dipolar DMFA is used as a solvent and used as a methylating agent, 1,3-dimethylquinazolin-4-one is also formed along with this compound.
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