IMMUNOHISTOCHEMICAL STUDIES IN THE CHOICE OF ADJUVANT CHEMOTHERAPY BREAST CANCER
DOI:
https://doi.org/10.5281/zenodo.7701116Keywords:
expression, histocompatibility, moleculesAbstract
Currently, breast cancer (BC) is the most common form of malignant tumors in women. At the same time, there is a whole field of immunologically assessed tumor parameters that have not yet been clearly reflected from the standpoint of the need to study them in each patient. This is, firstly, the immunophenotype of the tumor (expression of histocompatibility molecules of classes I and II, adhesion molecules, transferrin receptor, etc.), which has a direct relationship with tumor progression and antitumor immunity.Secondly, the levels and subpopulations of immunocompetent cells infiltrating breast cancer (this indicator can be useful in assessing the prognosis and in planning various immunotherapeutic measures).
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