Β-TRICALCIUM PHOSPHATE-BASED BONE MATERIALS AND THEIR APPLICATION IN THE TREATMENT OF ALVEOLAR RIDGE ATROPHY OF THE JAW
DOI:
https://doi.org/10.5281/zenodo.19387481Keywords:
β-TCP, bone graft substitute, alveolar ridge atrophy, osteoconduction, biomaterials, jawbone regeneration, dental implantsAbstract
Beta-tricalcium phosphate (β-TCP) is a synthetic, biocompatible, and resorbable calcium phosphate ceramic widely used in bone tissue engineering and regenerative dentistry. Its chemical composition and porous structure make it particularly suitable for alveolar bone regeneration in cases of jawbone atrophy. This thesis evaluates the physicochemical properties of β-TCP, its biological behavior, and clinical effectiveness in treating alveolar ridge resorption. The analysis is based on peer-reviewed scientific literature, focusing on osteoconductivity, biodegradation, and clinical outcomes. The findings confirm that β-TCP serves as an effective scaffold for new bone formation, especially in guided bone regeneration (GBR) and implantology.
References
Araujo M.G., Lindhe J. (2005). “Dimensional ridge alterations following tooth extraction.” Journal of Clinical Periodontology, Vol. 32, pp. 212–218.
Dorozhkin S.V. (2010). “Bioceramics of calcium orthophosphates.” Biomaterials, Vol. 31, pp. 1465–1485.
Nery E.B., et al. (2002). “Bioceramic implants in periodontal defects.” Journal of Periodontology, Vol. 73, pp. 123–130.
Schmitt C.M., et al. (2013). “Histological results after maxillary sinus augmentation.” Clinical Oral Implants Research, Vol. 24, pp. 576–585.
Jensen T., et al. (2009). “Bone graft materials in sinus augmentation.” Clinical Oral Implants Research, Vol. 20, pp. 123–131.
LeGeros R.Z. (2008). “Calcium phosphate-based osteoinductive materials.” Chemical Reviews, Vol. 108, pp. 4742–4753.
Knabe C., et al. (2008). “Resorption characteristics of β-TCP.” Biomaterials, Vol. 29, pp. 2249–2258.
Artzi Z., et al. (2004). “Histomorphometric analysis of bone regeneration.” Clinical Oral Implants Research, Vol. 15, pp. 558–565.
Cordaro L., et al. (2008). “Implant survival in augmented bone.” International Journal of Oral & Maxillofacial Implants, Vol. 23, pp. 1089–1096.
Jung R.E., et al. (2009). “Growth factors and bone regeneration.” Journal of Dental Research, Vol. 88, pp. 113–124.
Hing K.A. (2005). “Bioceramic bone graft substitutes.” Philosophical Transactions of the Royal Society A, Vol. 362, pp. 2821–2850.
Bose S., et al. (2013). “Recent advances in bone tissue engineering scaffolds.” Trends in Biotechnology, Vol. 31, pp. 594–605.
