PERINATAL INFEKSIYALAR VA NEVROLOGIK RIVOJLANISH BUZILISHLARI
DOI:
https://doi.org/10.5281/zenodo.18035351Keywords:
perinatal infektsiyalar, neonatologiya, markaziy nerv tizimi, nevrologik rivojlanish buzilishlari, kognitiv rivojlanish, motor rivojlanish, ijtimoiy rivojlanish, homilalik davri, tug‘ilganidan keyingi infektsiyalar, profilaktika, diagnostika, antibiotik terapiya, antiviral terapiya, emlash, prenatal skrining, yuqori xavfli omillar, bola salomatligi, perinatal davr, yangi tug‘ilgan chaqaloqlarAbstract
Perinatal infektsiyalar homila va yangi tug‘ilgan chaqaloqning nevrologik rivojlanishiga sezilarli ta’sir ko‘rsatadi va ularning rivojlanishdagi buzilishlariga olib kelishi mumkin. Bu infektsiyalar bakterial, virusli va parazitar agentlar tomonidan yuzaga keladi va homilalik davrida, tug‘ilganidan keyingi dastlabki kunlarda yoki dastlabki haftalarda markaziy nerv tizimiga ta’sir qilishi mumkin. Natijada motor, kognitiv, ijtimoiy va hissiy rivojlanishning turli darajadagi buzilishlari paydo bo‘lishi mumkin. Perinatal infektsiyalarning erta aniqlanishi va profilaktik choralar qo‘llanishi bolaning keyingi nevrologik rivojlanishini sezilarli darajada yaxshilashi mumkin. Shu bilan birga, maqolada infektsiyalarning turli shakllari, ularning markaziy nerv tizimiga ta’sir mexanizmlari, klinik belgilar, diagnostika usullari va zamonaviy profilaktika strategiyalari batafsil ko‘rib chiqilgan. Tadqiqotlar shuni ko‘rsatadiki, antibiotik va antiviral terapiya, emlashlar, prenatal skrining va xavfli omillarni boshqarish orqali perinatal infektsiyalar natijasida yuzaga keladigan nevrologik buzilishlar xavfini kamaytirish mumkin. Shu bois, perinatal infektsiyalar va ularning nevrologik rivojlanishga ta’siri pediatriya va neonatologiya amaliyotida dolzarb mavzu hisoblanadi.
References
Boppana, S. B., Ross, S. A., & Fowler, K. B. (2013). Congenital Cytomegalovirus Infection: Clinical Outcome. Clinical Infectious Diseases, 57(Suppl_4), S178–S181.
Rawlinson, W. D., et al. (2017). Congenital Cytomegalovirus Infection: Advances and Challenges in Diagnosis and Management. The Lancet Infectious Diseases, 17(6), e203–e212.
Kliegman, R., et al. (2020). Nelson Textbook of Pediatrics. 22nd Edition. Philadelphia: Elsevier.
Verboon-Maciolek, M. A., et al. (2006). Neonatal Viral Infections and Neurological Outcome. Seminars in Fetal and Neonatal Medicine, 11(5), 356–362.
Ades, A. E., et al. (2018). Group B Streptococcus in Pregnancy and Neonatal Disease: Prevention and Management. Pediatric Infectious Disease Journal, 37(1), 1–7.
Coyne, C. B., & Lazear, H. M. (2016). Zika Virus — Reigniting the TORCH. Nature Reviews Microbiology, 14, 707–715.
Sutcliffe, T., & Hines, R. (2019). Perinatal Infections and Neurodevelopmental Disorders. Current Opinion in Pediatrics, 31(6), 809–816.
Dunkel, I. J., & Fowler, K. B. (2017). Congenital Infections and Neurodevelopment. Clinics in Perinatology, 44(2), 229–246.
Waldorf, K. M., & McAdams, R. M. (2013). Impact of Maternal Infection on Fetal Brain Development. Current Opinion in Pediatrics, 25(2), 233–239.
Stoll, B. J., et al. (2011). Neonatal Sepsis and Neurodevelopmental Outcome. Pediatric Infectious Disease Journal, 30(1), 21–25..
A’zamxonovna, A. N. (2025). NAMANGAN VILOYATIDA MUSIQA MAKTABLARINING SHAKLLANISH TARIXIDAN. INNOVATIVE DEVELOPMENTS AND RESEARCH IN EDUCATION, 4(37), 45-51
