BIOPHYSICAL FOUNDATIONS OF ELECTROCARDIOGRAPHY (ECG) SIGNALS

Authors

  • Aynura Jumamuratova Teacher at the Aral region medical and transport technical college

DOI:

https://doi.org/10.5281/zenodo.18678257

Keywords:

Electrocardiography (ECG), cardiac electrophysiology, action potential, ion channels, depolarization, repolarization.

Abstract

In this thesis, the biophysical foundations of electrocardiography (ECG) signals are briefly analyzed at the cellular and tissue levels. The study explains how ionic currents of sodium (Na⁺), potassium (K⁺), and calcium (Ca²⁺) generate cardiac action potentials and how these electrical impulses propagate through the cardiac conduction system. The relationship between depolarization–repolarization processes and the main ECG components (P wave, QRS complex, and T wave) is also described. The work highlights the importance of biophysical mechanisms for accurate ECG interpretation and clinical application.

References

Willem Einthoven (1903). Die galvanometrische Registrierung des menschlichen Elektrokardiogramms. Pflügers Archiv für die gesamte Physiologie.

Denis Noble (1962). A modification of the Hodgkin–Huxley equations applicable to Purkinje fibre action and pacemaker potentials. The Journal of Physiology, 160(2), 317–352.

Andrew L. Hodgkin & Andrew F. Huxley (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. The Journal of Physiology, 117(4), 500–544.

Yoram Rudy & Chun Liu Luo (1991). A model of the ventricular cardiac action potential. Circulation Research, 68(6), 1501–1526.

American Heart Association (2020). Guidelines for Electrocardiography Interpretation. Circulation Journal.

European Society of Cardiology (2019). ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. European Heart Journal.

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Published

2026-02-17

How to Cite

Jumamuratova, A. (2026). BIOPHYSICAL FOUNDATIONS OF ELECTROCARDIOGRAPHY (ECG) SIGNALS. Academic Research in Modern Science, 5(6), 169-173. https://doi.org/10.5281/zenodo.18678257