PRESENCE OF AGE-RELATED COMORBID DISEASES IN THE POPULATION OF LONG-LIVING PEOPLE (REPRESENTATION OF AGE AS A RISK FACTOR)
DOI:
https://doi.org/10.5281/zenodo.17151047Abstract
The increase in life expectancy led to an increase in the number of gerontological patients with comorbid diseases, with at least 2 diseases simultaneously. Comorbidity is a risk factor leading to decreased function of various organs, the occurrence of cognitive impairments and geriatric syndromes, an increase in disability and premature mortality [1;2]. Comorbid diseases increase with age and sharply increase the risk of polypharmacy, as a result of which a second risk arises, especially for the gerontological population - the pharmacoepidemiological factor. In particular, the proportion of patients of gerontological age who took 10 or more medications per day for 5 years before death increased from 30% to 47% [3].
References
Ibadova M.U. Pathogenetic significance of metabolic syndrome in the formation of polymorbid diseases // Abstract of the dissertation of Doctor of Philosophy (PhD) in Medical Sciences. - 2021. -P. 3.
Horodinschi R.N., Stanescu A.M.A., Bratu O.G. et al. Treatment with statins in Elderly Patients//Medicina. (Kaunas). -2019. -Vol.55. -N.11. -P.720. DOI: 10.3390 /medicina 55110721. PMID: 31671689. PMCID: PMC6915405.
Morin L., Vetrano D.Sh., Rizzuto D. Et al. Choosing wisely? Measuring the burden of medications in older adults near the end of life: nationwide, longitudinal cohort study//Am. J. Med. -2017. -Vol.130. -N8. -5.922-934.
