KÒKRAK SARATONINING ANATOMIK VA KLINIK JIHATLARI O’RTASIDAGI O’ZARO BOG’LIQLIK
DOI:
https://doi.org/10.5281/zenodo.18397068Keywords:
ko‘krak saratoni, ko‘krak bezining anatomiyasi, klinik jihatlar, duktal karsinoma, lobulyar karsinoma, invaziv o‘sma, limfa tugunlari, metastaz, diagnostika, davolash strategiyalari, prognostik omillar.Abstract
Ushbu maqolada ko‘krak saratonining anatomik tuzilmalari va uning klinik kechishi o‘rtasidagi o‘zaro bog‘liqlik har tomonlama tahlil qilingan. Ko‘krak bezining asosiy anatomik komponentlari — lobulalar, sut yo‘llari, biriktiruvchi va yog‘ to‘qimalari hamda limfa tizimining o‘sma rivojlanishi va tarqalishidagi roli yoritib berilgan. O‘smaning anatomik kelib chiqishi, joylashuvi va invazivlik darajasining klinik h, diagnostika jarayoni va kasallik bosqichini aniqlashga ta’siri ko‘rib chiqilgan. Shuningdek, anatomik va klinik ma’lumotlarning uyg‘unligi asosida davolash strategiyalarini tanlash, jumladan jarrohlik aralashuvi hajmi va qo‘shimcha terapiya usullarini belgilashning ahamiyati ta’kidlangan. Tadqiqot natijalari ko‘krak saratonini erta aniqlash, prognozlash va individual davolash rejasini ishlab chiqishda anatomik-klinik yondashuv muhimligini ko‘rsatadi.
References
Bray F., Ferlay J., Soerjomataram I., Siegel R. L., Torre L. A., Jemal A. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 2021.
Kumar V., Abbas A. K., Aster J. C. Robbins and Cotran Pathologic Basis of Disease. 10th ed. Philadelphia: Elsevier, 2020.
Bland K. I., Copeland E. M., Klimberg V. S., Gradishar W. J. The Breast: Comprehensive Management of Benign and Malignant Diseases. 5th ed. Philadelphia: Elsevier, 2018.
DeVita V. T., Lawrence T. S., Rosenberg S. A. DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology. 11th ed. Philadelphia: Wolters Kluwer, 2019.
Harbeck N., Penault-Llorca F., Cortes J., et al. Breast cancer. Nature Reviews Disease Primers, 2019.
Schnitt S. J. Classification and prognosis of invasive breast cancer: from morphology to molecular taxonomy. Modern Pathology, 2010.
Donegan W. L., Spratt J. S. Cancer of the Breast. 5th ed. Philadelphia: Saunders, 2002.
National Comprehensive Cancer Network (NCCN). Clinical Practice Guidelines in Oncology: Breast Cancer. Latest edition.
Tavassoli F. A., Devilee P. (eds). World Health Organization Classification of Tumours of the Breast. Lyon: IARC Press, 2012.
Lakhani S. R., Ellis I. O., Schnitt S. J., Tan P. H., van de Vijver M. J. WHO Classification of Tumours of the Breast. 4th ed. Lyon: IARC, 2012..
