XOLESTERIN TASHILISHIDA QATNASHUVCHI APO OQSILLAR. YOG' BOSISH, SEMIRISH. SFINGOLIPIDOZLAR
DOI:
https://doi.org/10.5281/zenodo.18338489Keywords:
Apolipoproteinlar, Xolesterin tashilishi, Lipoproteinlar, Yog‘ bosish, Semirish, Lipid almashinuvi, Sfingolipidozlar, Metabolik kasalliklar, Energiya almashinuvi, Yurak-qon tomir kasalliklari.Abstract
Ushbu maqolada xolesterinning organizmda tashilishi jarayonida ishtirok etuvchi apolipoproteinlar (apo oqsillar)ning tuzilishi va biologik ahamiyati, ularning lipid almashinuvini boshqarishdagi roli yoritilgan. Shuningdek, yog‘ bosish va semirish jarayonlarining biokimyoviy mexanizmlari, energiya almashinuvi buzilishlari bilan bog‘liqligi tahlil qilingan. Maqolada sfingolipidozlar — sfingolipidlar almashinuvi buzilishi natijasida kelib chiqadigan irsiy metabolik kasalliklarning asosiy turlari, patogenezi va klinik ahamiyati ko‘rib chiqilgan. Ushbu mavzularning o‘zaro bog‘liqligi yurak-qon tomir kasalliklari va metabolik sindrom rivojlanishidagi ahamiyati nuqtai nazaridan tahlil etilgan. Maqola tibbiyot va biologiya yo‘nalishidagi talabalar hamda mutaxassislar uchun mo‘ljallangan.
References
Murray R.K., Bender D.A., Botham K.M. Harper’s Illustrated Biochemistry. 31st ed. McGraw-Hill Education, 2018.
Nelson D.L., Cox M.M. Lehninger Principles of Biochemistry. 7th ed. W.H. Freeman and Company, 2017.
Devlin T.M. Textbook of Biochemistry with Clinical Correlations. 7th ed. Wiley-Liss, 2011.
Rodwell V.W., Bender D.A., Botham K.M. Biochemistry. Elsevier, 2015.
G‘.G‘. Qodirov, N.A. Usmonov. Biokimyo. Toshkent: Abu Ali ibn Sino nomidagi tibbiyot nashriyoti, 2016.
Stryer L., Berg J.M., Tymoczko J.L. Biochemistry. 8th ed. W.H. Freeman, 2015.
Guyton A.C., Hall J.E. Textbook of Medical Physiology. 13th ed. Elsevier, 2016.
Scriver C.R., Beaudet A.L., Sly W.S. The Metabolic and Molecular Bases of Inherited Disease. McGraw-Hill, 2001.
Fauci A.S. et al. Harrison’s Principles of Internal Medicine. 20th ed. McGraw-Hill, 2018.
Kopelman P.G. Obesity as a Medical Problem. Nature, 2000
