DIAGNOSTIC AND PROGNOSTIC VALUE OF MATRIX METALLOPROTEINASES IN KIDNEY PATHOLOGY
DOI:
https://doi.org/10.5281/zenodo.18676753Keywords:
Matrix metalloproteinases; tissue inhibitors of metalloproteinases; inflammatory kidney diseases; chronic kidney disease; glomerulonephritis; renal tissue remodeling; extracellular matrix; molecular biomarkers; renal fibrosis.Abstract
This article presents an extended scientific rationale for the role of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in the development of inflammatory kidney diseases. Particular attention is paid to molecular mechanisms, pathophysiological alterations, and contemporary concepts of renal tissue remodeling, in accordance with the requirements of European scientific journals.
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