TUXUMDON KISTALARINI OLOB TASHLASHDA ENERGIYA ALMASHINUVI FERMENTLARI FAOLLIGINING KLINIK AHAMIYATI
DOI:
https://doi.org/10.5281/zenodo.18349602Keywords:
Tuxumdon kistalari, energiya almashinuvi, fermentlar faolligi, laktatdegidrogenaza (LDG), malatdegidrogenaza (MDG), jarrohlik stressi, gipoksiya, metabolik gomeostaz, klinik biokimyo.Abstract
Ushbu maqolada tuxumdon kistalarini jarrohlik yo‘li bilan olib tashlash amaliyoti davomida va undan keyingi davrda energiya almashinuvi fermentlari faolligining o‘zgarishi hamda ularning klinik ahamiyati tahlil qilinadi. Tadqiqotning asosiy e’tibori laktatdegidrogenaza (LDG), malatdegidrogenaza (MDG) va kreatinfosfokinaza (KFK) kabi asosiy metabolik fermentlarning qon zardobidagi va to‘qima darajasidagi dinamikasiga qaratilgan. Jarrohlik stressi natijasida yuzaga keladigan gipoksiya va to‘qimalarning tiklanish jarayonlarida ushbu fermentlarning diagnostik va prognostik roli o‘rganilgan. Olingan natijalar operatsiyadan keyingi asoratlarni barvaqt aniqlash va bemorlarni reabilitatsiya qilish strategiyasini optimallashtirish uchun biokimyoviy mezon bo‘lib xizmat qiladi.
References
Azziz, R., et al. (2024). Biochemical Markers in Ovarian Surgery: A Comprehensive Review. Journal of Clinical Endocrinology & Metabolism, 109(4), 812-828.
Gulyamov, S. S., & Alieva, N. M. (2023). Tuxumdon kistalarini olib tashlashda gipoksiya fermentlarining klinik ahamiyati. O‘zbekiston Tibbiyot Jurnali, 2-son, 45-51-betlar.
Berg, J. M., et al. (2023). Biochemistry of Energy Metabolism: LDH and MDH Function in Tissue Trauma. W.H. Freeman and Company, 10th Edition.
Clement, P. B., & Young, R. H. (2025). Atlas of Gynecologic Surgical Pathology. Elsevier Health Sciences.
Kasper, D. L., et al. (2024). Harrison's Principles of Internal Medicine: Metabolic Response to Surgery. McGraw-Hill Education.
Makarov, I. O., et al. (2023). Ovarian Reserve and Metabolic Homeostasis after Laparoscopic Cystectomy. International Journal of Gynecology & Obstetrics, 161(2), 234-245.
Nezhat, C., et al. (2024). Advanced Laparoscopy: Impact on Oxidative Stress and Enzyme Activity. Fertility and Sterility, 121(3), 410-422.
Power, M. L., & Schulkin, J. (2023). The Biochemistry of the Reproductive System. Cambridge University Press.
Sultanov, S. N. (2024). Ginekologik operatsiyalarda energiya almashinuvi ko'rsatkichlarining diagnostik tahlili. Toshkent Tibbiyot Akademiyasi Axborotnomasi, 1-son, 78-83-betlar.
Tretter, L., & Adam-Vizi, V. (2023). The Role of Malate Dehydrogenase in Mitochondrial Bioenergetics during Ischemia. Neurochemistry International, 166, 105-119.
Vasiliev, A. V. (2025). Clinical Biochemistry of Muscle and Tissue Damage Markers (CPK) in Surgery. Clinical Chemistry and Laboratory Medicine (CCLM), 63(1), 15-29.
Zhu, J., & Li, Y. (2024). Postoperative Metabolic Recovery and Antioxidant Therapy in Gynecological Patients. Journal of Biological Chemistry, 300(2), 112-126.
